Sodium hyaluronate CAS#9067-32-7

CAS Number: 9067-32-7

Chemical Formula: C14H22NNaO11

Synonyms:

  cockscomb;Hyaluronesodium

  hyaluronic

  Si-4402

Appearance: White to off-white powder or granules

HS Code: 39139000

MOQ (Minimum Order Quantity): 1 FCL (Full Container Load)


Product Details

Products Description of Sodium hyaluronateCAS#9067-32-7

Also known as sodium glycosaminoglycan, sodium hyaluronate is a physiologically active substance naturally present in the human body. It is a high-molecular-weight linear mucopolysaccharide made up of glucuronic acid and acetylated hexosamine disaccharide units, with a molecular weight of 1 million. It dissolves in water to form a viscous, elastic solution with physiological acidity and ionic strength. Its variable molecular form enables injection via a finer syringe. The non-inflammatory extract of sodium hyaluronate is called Healon. Dissolving 10mg of Healon in 1ml of physiological saline results in a viscosity 200,000 times higher than that of aqueous humor or physiological saline. Healon has a protein content below 0.5% and is a sterile, highly pure solution.


Parameters

Melting point 

>209°C (dec.)

alpha 

D25 -74° (c = 0.25 in water):   Rapport et al., J. Am. Chem. Soc. 73, 2416 (1951)

storage temp. 

-20°C

solubility 

H2O: 5 mg/mL,   clear, colorless

form 

Powder or granules

color 

White to off-white

PH

pH(2g/l,25℃) : 5.5~7.5

biological source

chicken (rooster comb)

Water Solubility 

SOLUBLE

Merck 

13,4776

Stability:

Stable. Incompatible with   strong oxidizing agents.

InChI

InChI=1/C14H23NO11.Na/c1-4(17)15-5-2-6(18)7(3-16)24-14(5)26-10-8(19)9(20)13(23)25-11(10)12(21)22;/h5-11,13-14,16,18-20,23H,2-3H2,1H3,(H,15,17)(H,21,22);/q;+1/p-1/t5-,6+,7-,8-,9-,10+,11+,13-,14+;/s3

InChIKey

MAKUBRYLFHZREJ-JWBQXVCJSA-M

SMILES

[C@@H]1(O[C@H]2[C@H](O)[C@H]([C@H](O)O[C@@H]2C(=O)[O-])O)O[C@H](CO)[C@@H](O)C[C@H]1NC(=O)C.[Na+]   |&1:0,2,3,5,6,9,15,18,21,r|

LogP

-6.623 (est)

CAS DataBase Reference

9067-32-7(CAS DataBase   Reference)

 

 Safety Information

Hazard Codes 

B,Xi

Risk Statements 

36/37/38

Safety Statements 

22-24/25-36/37/39-27-26

WGK Germany 

3

RTECS 

MT7250000

3-10

HS Code 

39139000

Toxicity

LD50 oral in rabbit: >   1gm/kg


Product Application of  Sodium hyaluronateCAS#9067-32-7

Due to its outstanding moisturizing, anti-aging, repair and lubricating properties, sodium hyaluronate is widely used in various fields:

Cosmetics and skincare: As a top moisturizing ingredient, it is widely used in facial creams, serums, masks and other skin care products, helping to relieve dryness and tightness, maintaining skin moisture and improving fine lines.

Medicine and clinical applications:

Orthopedics: Used for intra-articular injection for arthritis to lubricate joints, relieve pain and promote cartilage matrix synthesis.

Ophthalmology: As an artificial tear or surgical auxiliary medication, it is used to relieve eye dryness and protect corneal endothelium.

Wound healing: Participates in tissue remodeling, promoting the healing of fresh wounds and chronic ulcers.

Research fields: As a main component of extracellular matrix (ECM), it is used in research on cell signal transduction, tumor physiology (such as cell proliferation, migration, angiogenesis) and the development of tissue engineering scaffolds.


Factory and Equipment Show

 5f5b1d44cca56fd5ce85d86dfa133a9f.jpg 


Fast delivery time

Inventory 2-3 working days New production 7-10 working days

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