L-Leucine CAS#61-90-5
L-leucine is one of the eight essential amino acids and falls into the category of aliphatic amino acids among the twenty proteinogenic amino acids. It is grouped with L-isoleucine and L-valine as the three branched-chain amino acids, and it is the enantiomer of D-leucine. Since the human body cannot synthesize it on its own, it must be obtained through diet or supplements.
L-Leucine Chemical Properties
Melting point | >300 °C (lit.) |
alpha | 15.4 º (c=4, 6N HCl) |
Boiling point | 122-134 °C(Press: 2-3 Torr) |
bulk density | 300-400kg/m3 |
density | 1,293 g/cm3 |
vapor pressure | <1 hPa (20 °C) |
refractive index | 1.4630 (estimate) |
FEMA | 3297 | L-LEUCINE |
Fp | 145-148°C |
storage temp. | 2-8°C |
solubility | 1 M HCl: 50 mg/mL |
form | powder |
pka | 2.328(at 25℃) |
color | White |
Odor | at 100.00?%. odorless |
PH | 5.5-6.5 (20g/l, H2O, 20℃) |
biological source | plant |
Optical Rotation | [α]20/D +15.5°, c = 2 in 6 M HCl |
Water Solubility | 22.4 g/L (20 C) |
λmax | λ: 260 nm Amax: 0.05 |
JECFA Number | 1423 |
Sublimation | 145-148 ºC |
Merck | 14,5451 |
BRN | 1721722 |
Stability: | Stability Moisture and light sensitive. Incompatible with strong oxidising agents. |
LogP | 0.80 |
CAS DataBase Reference | 61-90-5(CAS DataBase Reference) |
NIST Chemistry Reference | Leucine(61-90-5) |
EPA Substance Registry System | L-Leucine (61-90-5) |
Safety Information
Safety Statements | 24/25 |
WGK Germany | 3 |
RTECS | OH2850000 |
TSCA | Yes |
HS Code | 29224995 |
Hazardous Substances Data | 61-90-5(Hazardous Substances Data) |
Product Application of L-Leucine CAS#61-90-5
Sports nutrition and dietary supplements: This is the most widespread application area of L-leucine. It is widely used in protein powders, muscle-building powders, and specialized BCAA (branch-chain amino acid) supplements, helping athletes build muscle, lose fat, and relieve fatigue.
Medicine and clinical nutrition: In clinical settings, L-leucine is often combined with other amino acids to form compound amino acid injections for intravenous nutritional support. Additionally, it is also used to treat certain metabolic diseases, liver diseases, and to improve sarcopenia (muscle loss) in the elderly.
Food industry: As a nutritional fortifier, L-leucine acid is added to infant formula foods, special medical foods, and some functional beverages to enhance the overall nutritional value of the food.
Biochemical research and cosmetics: In biochemical experiments, it is used as a component of culture media; in cosmetics, it can be used as a skin conditioning agent and has certain moisturizing and anti-wrinkle auxiliary functions.
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