Sodium 4-aminosalicylate dihydrate

Sodium 4-aminosalicylate dihydrate CAS#6018-19-5

Sodium 4-aminosalicylate dihydrate, frequently employed as an anti-tuberculosis medication, goes by alternative names including 4-amino-2-hydroxybenzoate dihydrate sodium and PAS-Na. This compound appears as a white or off-white crystalline powder, characterized by no odor, a sweet-salty taste, high solubility in water, slight solubility in ethanol, poor solubility in acetone, and nearly no solubility in ether, chloroform, or benzene. A 2% aqueous solution of this substance has a pH range of 6.5 to 8. Notably, its aqueous solution tends to decarboxylate into m-aminophenol, making fresh preparation necessary prior to use.

Sodium 4-aminosalicylate dihydrate Chemical Parameters

Sodium 4-aminosalicylate dihydrate CAS#6018-19-5 Application

This medication is indicated for pulmonary and extrapulmonary tuberculosis induced by Mycobacterium tuberculosis. Active solely against mycobacteria—not non-tuberculous mycobacterial strains—it is prone to rapid development of drug resistance if administered alone, hence the requirement for combination therapy with other anti-tuberculosis agents. When combined with streptomycin or isoniazid, it helps delay the emergence of Mycobacterium tuberculosis resistance to these two drugs. Primarily classified as a second-line anti-tuberculosis drug, it also finds application in treating hyperthyroidism, particularly suitable for patients concurrently diagnosed with hyperthyroidism and tuberculosis. In cases where iodine therapy proves ineffective or interferes with surgical procedures, short-term administration can facilitate preoperative preparation. For severe conditions such as tuberculous meningitis, intravenous infusion of the injectable formulation is typically recommended.

Factory Show

As an ISO-certified chemical exporter with 15 years of professional experience, we leverage leading production technology, advanced equipment, and a professional team to provide high-quality chemical raw materials to over 2,000 companies worldwide. Our products are widely used in pharmaceuticals, agriculture, food manufacturing, and industrial production, with business spanning six continents. We are committed to providing reliable supply chain support and solutions to customers across various industries.

1. 
   

   Fast delivery time

2. Inventory 2-3 working days New production 7-10 working days