Products Description of Idebenone CAS# 58186-27-9
Idebenone belongs to the 1,4-benzoquinone class of compounds. Its chemical structure is characterized by methoxy groups substituted at the 2- and 3-positions, a methyl group at the 5-position, and a 10-hydroxydecyl group at the 6-position. Initially developed for the treatment of Alzheimer's disease, it demonstrated only modest therapeutic benefits. Subsequently, it was found to be effective for the symptomatic treatment of Friedreich's ataxia. Idebenone functions as an antioxidant and a ferroptosis inhibitor, and it is classified as both a primary alcohol and a 1,4-benzoquinone derivative.
Parameters
Melting point | 52-550C |
Boiling point | 497.3±45.0 °C(Predicted) |
density | 1.08±0.1 g/cm3(Predicted) |
storage temp. | room temp |
solubility | Soluble in DMSO (up to 25 mg/ml). |
form | Solid |
pka | 15.20±0.10(Predicted) |
color | Orange |
Merck | 14,4888 |
Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
InChI | InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3 |
InChIKey | JGPMMRGNQUBGND-UHFFFAOYSA-N |
SMILES | C1(=O)C(OC)=C(OC)C(=O)C(C)=C1CCCCCCCCCCO |
LogP | 3.490 (est) |
CAS DataBase Reference | 58186-27-9(CAS DataBase Reference) |
Safety Information
Hazard Codes | Xi |
WGK Germany | 3 |
RTECS | GU5290000 |
HS Code | 2933399990 |
Product Application of Idebenone CAS# 58186-27-9
Idebenone acts as an antioxidant that can shield the skin from damage caused by various free radicals—including preventing the formation of secondary chemicals that exert adverse effects on skin physiology. It is reported to alleviate both intrinsic and extrinsic skin damage induced by free radical generation. As a synthetic analog of coenzyme Q10, idebenone boasts a smaller molecular structure.
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Inventory 2-3 working days New production 7-10 working days
