Petrolatum

alpha 

D25 -165° (c = 1 in water) (calc for water-free substance)

refractive index 

-160 ° (C=1, H2O)

storage temp. 

Keep in dark place,Inert atmosphere,2-8°C

solubility 

H2O: soluble50mg/mL

pka

~3 (COOH), 3.2 (NH3+), 4.1 (enolic OH)

form 

powder or crystals

color 

White to Off-White

Water Solubility 

Freely soluble in water

InChIKey

FDRNWTJTHBSPMW-BBJOQENWSA-L

Safety Information

Hazard Codes 

Xn

Risk Statements 

36/37/38-42/43

Safety Statements 

26-36-45-37-24-22

WGK Germany 

1

RTECS 

XI0368800

HS Code 

29349990

Toxicity

LD50 in male, female, mice, rats (mg/kg): 3000, 2800, 2175, 2175 i.v.; >10000 all species orally; >5000 all species s.c. (Teelman)

MSDS Information

Provider

Language

SigmaAldrich

English

Ceftriaxone sodium Usage And Synthesis

Description

Ceftriaxone is a third-generation, broad-spectrum cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It has been shown to increase excitatory amino acid transporter-2 pump expression in the central nervous system and to reduce glutamatergic toxicity in both in vitro and in vivo models.

Chemical Properties

White Crystalline Solid

Uses

antipsychotic

Uses

A potentially useful antibacterial agent for proteomics research.

Uses

An antibacterial, a third-generation cephalosporin.

Definition

ChEBI: Ceftriaxone disodium salt hemiheptahydrate is a cephalosporin.

Brand name

Rocephin (Roche).

Biological Activity

β -lactam antibiotic. Displays neuroprotective activity in vivo via upregulation and increased activity of the EAAT2 glutamate transporter.