4-Fluorobenzaldehyde CAS#459-57-4
Product Application of 4-Fluorobenzaldehyde CAS#459-57-4
4-Fluorobenzaldehyde (CAS#459-57-4) is a significant organic synthesis intermediate, typically appearing as a colorless to pale yellow liquid with a characteristic aromatic odor. It exhibits the typical chemical properties of an aldehyde, undergoing reactions such as oxidation, reduction, and condensation. The incorporated fluorine atom introduces distinct reactivity, making the compound a unique reactive site in synthetic applications.
Parameters
Melting point | -10 °C (lit.) |
Boiling point | 181 °C/758 mmHg (lit.) |
density | 1.157 g/mL at 25 °C (lit.) |
vapor pressure | 19 hPa (70 °C) |
refractive index | n20/D 1.521(lit.) |
Fp | 134 °F |
storage temp. | Store below +30°C. |
solubility | Chloroform, Methanol |
form | Liquid |
color | Clear colorless to yellow |
Specific Gravity | 1.157 |
Water Solubility | IMMISCIBLE |
Sensitive | Air Sensitive |
BRN | 385857 |
Stability: | Air Sensitive |
InChIKey | UOQXIWFBQSVDPP-UHFFFAOYSA-N |
CAS DataBase Reference | 459-57-4(CAS DataBase Reference) |
NIST Chemistry Reference | Benzaldehyde, 4-fluoro-(459-57-4) |
EPA Substance Registry System | Benzaldehyde, 4-fluoro- (459-57-4) |
Safety Information
Hazard Codes | Xi,F |
Risk Statements | 36/37/38 |
Safety Statements | 26-36-37/39-36/37/39-27 |
RIDADR | UN 1989 3/PG 3 |
WGK Germany | |
F | 9-23 |
Hazard Note | Flammable |
TSCA | T |
HazardClass | 3.2 |
PackingGroup | III |
HS Code | 29130000 |
Product Application of 4-Fluorobenzaldehyde CAS#459-57-4
4-Fluorobenzaldehyde, a fluorinated benzaldehyde, exhibits inhibitory activity against mushroom tyrosinase. It serves as a key synthetic intermediate, notably in the preparation of a pyrazolopyridine derivative that acts as a mitogen-activated protein kinase (MAPK) inhibitor. Its broader applications also include the synthesis of various pharmaceutical compounds.
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